The MCRC is affiliated with the following research bases:

• North Central Cancer Treatment Group (NCCTG) - Mayo Clinic
• Eastern Cooperative Oncology Group (ECOG)
• National Surgical Adjuvant Breast and Bowel Project (NSABP)
• Southwest Oncology Group (SWOG)
• Radiation Therapy Oncology Group (RTOG)
• MD Anderson CCOP Research Base (MDA)
• Cancer Trials Support Unit (CTSU)
• Gynecology Oncology Group (GOG)
• Wake Forest University (WFU)