Clinical Trials Search
The Influence on Time to Progression of Adriamycin + Dexrazoxane vs No Treatment in Female Patients with Advanced or Metastatic Breast Cancer After Treatment with Six Courses of CAF
880-50
- Eligibility:Click Here to View1.0) Adjuvant chemo =6 mo prior is OK.
2.0) No Anthracyclines.
3.0) No chemo for mets allowed.
4.0) Prior RT OK.
5.0) No CNS mets.
Drugs: CAF, Dexrazoxane(provided) - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
A Trial of Adjuvant Chemoradiation After Gastric Resection for Adenocarcinoma, Phase III
90-41-51
- Eligibility:Click Here to View1.0) Path (+) adeno of stomach or GE junction.
2.0) Must have had "en bloc" resection of all tumor and be at high risk for later failure.
3.0) No ascites, peritoneal seeding, liver mets or extra-ABD mets.
4.0) 20-40 days postop to registration
5.0) PS 0-2.
6.0) No prior RT, chemo or immunotherapy.
Drugs: 5-FU, Leucovoren
7.0)
8.0) - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior To Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients With High-Risk, Clinically Localized Prostate Cancer
90203
- Eligibility:Click Here to View
-Histologically confirmed adenocarcinoma of the prostate
-No small cell, neuroendocrine, or transitional cell carcinoma
-Clinically localized, stage T1-3a disease
-No radiographic evidence of metastatic disease
-Serum prostate-specific antigen level <= 100 ng/mL within the past 6 weeks
-Patients must have high-risk disease determined by EITHER--
--Probability of biochemical progression-free survival at 5 years after surgery < 60% by Kattan nomogram prediction or
--Prostate biopsy gleason sum greater than or equal to 8
-Patients must be deemed an appropriate candidate for radical prostatectomy
-No prior treatment for prostate cancer, including surgery, pelvic lymph node dissection, radiotherapy, or chemotherapy
-ECOG performance status 0-2 - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
Phase II Trial: Evaluation of the Role of Multiple Metastasectomy Combined with Systemic and Hepatic Artery Infusion Chemotherapy for Colorectal Carcinoma Metastatic to the Liver
92-46-52
- Eligibility:Click Here to View1.0) Ability to withstand operative procedure.
2.0) Patients may have received prior adjuvant 5FU with or without levamisole and/or leucovorin.
Drugs: Floxuridine, 5-FU, Leucovorin - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
A Phase I/II Dose Escalation Study using Thre Dimensional Conformal Radiation Therapy in Patients with Inoperable, Non-Small Cell Lung Cancer
93-11
- Eligibility:Click Here to View1.0) Stage I-IIIB (unresected).
2.0) PS >70
3.0) No malignant pleural effusion, positive supraclavicular nodes, or massive atelectasis. - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
A Randomized Phase II Trial of Different Schedules of Topotecan for the Treatment of Extensive-Stage Small Cell Lung Cancer
93-20-53
- Eligibility:Click Here to View
- Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
Phase I/II Study of Chemo-Radiotherapy Used Pre-Operatively or Definitively in Carcinoma of the Esophagus or GE Junction
94-474
- Eligibility:Click Here to View1.0) Path (+) squamous cell or adeno CA of esopha/GE junction
2.0) T1-2,Nx-N1,M0.
3.0) PS 0-2.
Drugs: Cisplatinum, 5FU - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
Phase I/II Study of Post-Cryosurgery (Salvage) Radiotherapy in Carcinoma of the Prostate
94-476
- Eligibility:Click Here to View1.0) Residual tumor in prostate, periprostatic tissue following definitive cryosurg.
2.0) PS 0-2
3.0) No prior pelvic RT
Drug: Not applicable - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
Colorectal Adenoma Chemoprevention Trial Using Aspirin: A Phase III Study
94-92-51
- Eligibility:Click Here to View1.0) Path (+) colon or rectal cancer.
2.0) Age >30 and <75.
3.0) No current chemo or RT.
4.0) No NSAID use or contraindications to aspirin use.
5.0) No familial polyposis, active malignancy or inflammatory bowel dz
6.0)
7.0) No immunosuppressive therapy w/in 6 mo. preceeding study entry.
Drug: Aspirin (provided) - Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.
Phase III Double-Blind Placebo-Controlled Trial to Assess the Effectiveness of Sucralfate in the Prevention of Treatment-Induced Diarrhea in Patients Receiving Pelvic Radiation Therapy
94-92-52
- Eligibility:Click Here to View
- Consent forms:You must be logged in to view the documents.
- Protocols:You must be logged in to view the documents.